Seditol is an all-natural blend of a patented extract from Magnolia officinalis U.S. Patent No. 6,814,987) and a proprietary extract from Ziziphus spinosa. Both plant extracts have played a major role in traditional Chinese medicine for over 1,500 years. In central nervous system receptor binding assays, one of the ingredients in Seditol binds to several important targets associated with drowsiness, including adenosine A1 and GABA.

A recent study at the Sleep Research and Treatment Center, Department of Psychiatry, Pennsylvania State University College of Medicine has demonstrated that the leading cause of sleeplessness in otherwise healthy adults is an overactive central nervous system with associated elevation of stress hormones. The scientists concluded from this study that the therapeutic goal in sleeplessness should be to decrease the level of physical and emotional arousal, and not just improve nighttime sleep. Seditol was developed to uniquely address the need to decrease nighttime physical and emotional arousal while providing a feeling of relaxation and less worry.